Sign In with your
Trend Micro Account
Need Help?
Need More Help?

Create a technical support case if you need further support.

Windows Defender and Apex One/OfficeScan compatibility

    • Updated:
    • 31 Dec 2021
    • Product/Version:
    • Apex One
    • Apex One All
    • Apex One as a Service
    • OfficeScan 11.0
    • OfficeScan 11.0
    • OfficeScan XG
    • Platform:

Running Apex One/OfficeScan and Windows defender on the same machine can lead to the following effects:

  • Slow login
  • Application lockup
  • Machine unresponsiveness/hang

You may refer to this documentation for updated Microsoft Window's Compatibility to 3rd party Antivirus. Recommended settings are indicated as well.

If any issue persists, Trend Micro recommends the following to resolve compatibility issues encountered with Windows Defender and Apex One/OfficeScan:

Trend Micro recommends deactivating Windows Defender to lessen resource consumption for your endpoints as well as ensure that Apex One/OfficeScan's security features works in optimal condition by eliminating potential conflicts with Windows Defender. The best way to do this is to deactivate Windows Defender globally via the Microsoft Group Policy Management (GPO) when using Apex One/OfficeScan.

  1. On the Server Manager Dashboard, click Tools, then click Group Policy Management.

    You may also use Windows key + R > gpmc.msc to open the Group Policy Management folder.

    Select Group Policy Management

  2. Navigate to Group Policy Management > Forest > Domains > your Domain > Group Policy Objects  then go to the Policy that needs to be adjusted.

    Right-click the target policy, then click Edit. The Group Policy Management Editor window will appear.

    Edit the policy

    For illustration purposes, the image shows making changes to the Default Domain Policy. You may create an additional policy instead of modifying the Default Domain Policy.
  3. Navigate to Computer Configuration > Policies > Windows Settings > Administrative Templates Policy definitions > Windows Components > Windows Defender.

    In the Windows 10 April 2018 Update, this path was changed from Windows Defender to Windows Defender Antivirus. The path listed here was subject to change along with the Windows update. Please get the GPO reference file from Microsoft and look for correct path here: Group Policy Settings Reference for Windows and Windows Server.

    The Windows Defender page will appear.

    Go to Windows Defender folder

  4. Under Settings, click Turn off Windows Defender. When the Turn off Windows Defender window appears, tick the Enabled radio button, click Apply then click OK.

    Set Turn off Windows Defender to Enabled

The Domain member machines will pick up the settings after the next reboot or you can update them immediately using ‘Windows key + R’ > ‘gpupdate /force’.

Trend Micro aims to continuously improve the compatibility and performance of Apex One/OfficeScan; it is recommended to do any of the following:

If the problem persists, please contact Trend Micro Technical Support for further assistance.
Solution Id:
Did this article help you?

Thank you for your feedback!

*This form is automated system. General questions, technical, sales, and product-related issues submitted through this form will not be answered.

If you need additional help, you may try to contact the support team. Contact Support

To help us improve the quality of this article, please leave your email here so we can clarify further your feedback, if neccessary:
We will not send you spam or share your email address.

*This form is automated system. General questions, technical, sales, and product-related issues submitted through this form will not be answered.