To resolve this issue:

1. In the Edge Relay server, run the following PS script as administrator to identify the certificates that need to be moved:

   Get-Childitem cert:\LocalMachine\root -Recurse | Where-Object {$_.Issuer -ne $_.Subject} | Format-List * | Out-File "c:\unsigned-certs.txt"

2. Move the non-self-signed certificate generated in unsigned-certs.txt from "Trusted Root Certification Authorities" to “Intermediate Certification Authorities”:
   1. On the Edge Relay server, click Start, type "mmc.exe" in the Start Search box and right-click mmc.exe, then click Run as administrator.
       

      If you are prompted for an administrator password or for a confirmation, type the password or click Continue.

       
   2. On the File menu, click Add/Remove Snap-in.
   3. Under Available snap-ins, click Certificates and then click Add.
   4. Click Computer account and then click Next.
   5. Click Local computer, then click Finish, and then click Close.
   6. To exit the wizard, click OK.
   7. Expand Certificates, then expand “Trusted Root Certification Authorities”.
   8. Right-click Certificates and then point to Cut.
   9. Go to Intermediate Certification Authorities > Certificates and then right-click Paste.
   10. Ensure that the non-self-signed certificate generated in unsigned-certs.txt” has been successfully moved to “Intermediate Certification Authorities”.

       URL: https://support.microsoft.com/en-us/help/942061/error-message-when-you-visit-a-web-site-that-is-hosted-on-iis-7-0-http

3. Perform to connect once more your Edge Relay Server from OSCE Server console.