If user enables BitLocker to protect a drive which is indicated by "Lock Status: Locked", the drive’s contents will not be accessible in any condition. In this scenario, Portable Security or boot scanning (Rescue Disk) will not be able to access the drive’s content to do any kind of operation.

Users can verify the lock status either by Graphical View of File Explorer:

Graphical view of locked drive

It can also be verified via the Command Prompt using manage-bde a command-line tool provided by BitLocker:

Lock Status: Locked

If a user sets the drive’s lock status to "Unlock", its contents will be accessible to the user or Portable Security.

Users can verify if the drive is Unlocked through the Graphical View of File Explorer:

Graphical view of unlocked drive

It can also be verified using the command manage-bde:

Lock Status: Unlocked