From the SMS:

1. Select a different DV
2. Activate selected DV
3. Distribute Profile to device

From the TPS LSM:

1. Download a DV package from TMC.
2. If you are not already on the System > Update > System, Update Licenses, navigate to that page.
3. In the Digital Vaccine Packages section, click Install to install the DV update.
4. Browse to select the DV update package file that you downloaded from the Threat Management Center.
5. Click Install to install the DV update.
6. While the new file is loaded onto your IPS device, an Update Progress page displays the update's current status. After the installation completes, you are returned to the System, Update Licenses page. The new version is displayed in the Digital Vaccine Packages section.