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To resolve the error:

 
Right-click the ClnPack.exe file and click on Run as Administrator.
 
  1. On the Windows 2008 Server, run OfficeScan 10.5 Server and open Server Manager.
  2. On the left hand pane menu, click Roles > Select Web Server (IIS). 
  3. Find Role Services and select Add Role Services.
  4. Enable Management Tools (IIS Management Console, IIS Management Scripts and Tools, Management Service).
  5. Enable IIS 6 Management Compatibility (IIS 6 Metabase Compatibility, IIS WMI Compatibility, IIS 6 Scripting Tools,IIS 6 Management Console).
  6. Click Next. 
  7. Click Install.
  8. Once the services are installed, run the Client Packager utility to create the MSI installer package.
 
Restart the server when required.
 

If the issue persists, collect the IIS Logs/CDT Logs and contact Trend Micro Technical Support or your Technical Account Manager.

Keywords: client package cannot be created,create msi file,MSI package error