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The issue is due to incorrect permissions on the OfficeScan server. To resolve the issue:

  1. On the OfficeScan server, open the IIS Manager.
  2. Navigate to Server > Sites > OfficeScan > officescan > hotfix_admin.
  3. Under the Features View, double-click Handler Mappings.

    Handler Mappings

  4. On the Actions pane, click Edit Feature Permissions. The Edit Feature Permissions dialog box appears.

    Edit Feature Permissions

  5. Tick the Script checkbox and click OK.

    Script

  6. Restart the IIS and OfficeScan Master Service.
  7. Perform a component update on clients.
  8. Verify that the clients automatically upgrade to the latest version and/or build number.