Do the following:

1. Open the IIS Manager.
2. Expand [Server name] > Web Sites > OfficeScan.
3. Right-click OfficeScan and then select Delete.
4. Click Yes when the confirmation message appears.
5. Go to the \Program Files\Trend Micro\OfficeScan\PCCSRV directory.
6. Run the following commands:
   svrsvcsetup –setvirdir
   svrsvcsetup –setprivilege
   svrsvcsetup –enablessl (only if you are using SSL to access the OfficeScan/WFBS server console)
7. Open Internet Explorer.
8. Go to Tools > Internet Options.
9. On the General tab, click Delete Cookies and then click OK.
10. Click Delete Files…
11. Select Delete all offline content and then click OK.
12. Click Clear History and then click Yes.
13. Click OK.
14. Close all the open Internet Explorer windows.
15. Restart the Microsoft IIS Web Server either via the command line or Control Panel.
    Command line
    1. Open a command prompt.
    2. Run this command: "IISRESET"
    Control Panel
    1. Go to Start > Settings > Control Panel
    2. Restart the WWW Publishing Service.
16. Restart the Trend Micro OfficeScan Master Service.
17. Try to launch the OfficeScan management console again.

• Case Diagnostic Tool (CDT) log generated on the OfficeScan server. Follow the steps in this KB article: How to use the Case Diagnostic Tool (CDT).
• Copy of the Internet Information Services (IIS) log.
  • For IIS 7.0:
    ..\Inetpub\wwwroot\logfiles\W3SVCnumber\exyymmdd.log
  • For IIS 6.0:
    %windir%\System32\LogFiles\W3SVCnumberexyymmdd.log
  References:
  • For IIS 6.0: Description of Microsoft Internet Information Services (IIS) 5.0 and 6.0 status codes
  • For IIS 7.0: The HTTP status codes in IIS 7.0