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The error indicates that the agent recognizes an invalid or untrusted certificate. This happens when there is a proxy server in between that decrypts HTTPS traffic. The said proxy server sends its own certificate to the agent, which the agent does not trust.

To resolve the issue, exclude the Smart Protection Server's URL (https://ds96.icrc.trendmicro.com/tmcss) from the HTTPS scanning list of the proxy server.