Deep Security Manager is able to support global IPv6 address, but it does not support a link-local IPv6 address due to encoding limitation.
If DSM is configured with a link-local IPv6 address (e.g. fe80::ec5a:896f:4a13:c26a%12), the Deep Security Agent will not be able to connect to DSM via URL http://<IPv6>:4120.
Currently, there is no plan to support it.