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When you go to Directories > Products from the Apex Central web console, you have your Apex One server managed under the Local Folder > New Entity folder.

 
Newly registered Apex One server is automatically placed by default in the New Entity folder. As a result and by design, the policies will not apply to any Trend Micro products under the default folder.
 

Checking the Policies > Policy Management. You will see the following blue banner:

Blue Banner

Click the image to enlarge.

To address the issue, you will need to create a new container. Do the following:

  1. From the Apex Central Console, go to Policies > Policy Management > Manage Product Directory.
     
    As an alternative, you can go to Directories > Products > Directory Management.
     
  2. Click Add Folder to create a new container, and provide a display name (e.g. APEX).
  3. From the default folder, drag the Apex One display name to the newly-created folder, then click Save.
  4. Go back to the Policy Management page and check if the Apex One agents can be selected under the new container.

For a complete overview over all needed requirement to deploy policies from Apex Central to it’s connected entities, refer to the following article: Policy management requirements for Apex Central.