The issue may have been caused by failed authentication due to these parameters: database.SqlServer.authenticationScheme=JavaKerberos and database.SqlServer.integratedSecurity=true.

To confirm the cause of the issue, review the server0.log under the Deep Security Manager's installation directory and check if it shows the following:

WARNING: ThID:16|TID:0|TNAME:Primary|UID:-1|UNAME:|Unable to connect to the database. Retrying in 10 seconds.  com.microsoft.sqlserver.jdbc.SQLServerException: Cannot login with Kerberos principal sa, check your credentials. Kerberos Login failed: Integrated authentication failed. ClientConnectionId:xxxxxxxx-xxxx-xxxx-xxxx-xxxxxxxxxxxx due to javax.security.auth.login.LoginException (KrbException: Cannot locate default realm)

To resolve the issue:

1. Go to Start > Run then type "services.msc".
2. Stop the Trend Micro Deep Security Manager service.
3. Go to the C:\Program Files\Trend Micro\Deep Security Manager\webclient\webapps\ROOT\WEB-INF folder and open the dsm.properties file.
4. Change "database.SqlServer.integratedSecurity=true" to "database.SqlServer.integratedSecurity=false".
5. Start the Trend Micro Deep Security Manager service.