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Please check the log file, C:\Program Files\Trend Micro\Smex\SMEX_DatabaseCreation.log

If there are multiple entries of:
CScript Error: Windows Script Host access is disabled on this machine. Contact your administrator for details.

Then please follow the procedure below to enable Windows Script Host access, to allow the installation to complete.

Enabling Windows Script Host
  1. Open the Run or Search menu by either pressing the Windows key or clicking start and locating the white box
  2. In the search field, type regedit.exe and press Enter to open the Registry Editor.
  3. Navigate to the following registry key by clicking through the menus on the left side:
    1. HKEY_LOCAL_MACHINE\Software\Microsoft\Windows Script Host\Settings
  4. On the right side of the Registry Editor window, double-click the Enabled registry value.
  5. if Enabled value is set to 0 this is disabled. Change it to a 1 to enable Windows Script Host.
  6. Close the Registry Editor window.
Once enabled the install should complete without error.


If the Cscript error above is not present in the SMEX_DatabaseCreation.log, please open a support can investigate further.