Upon investigation, Trend Micro determined that the recently released TMASE pattern version 27126.006 caused the TMASE engine in certain products to crash, which resulted in deferred or delayed emails on affected systems.  This pattern was removed from Trend Micro's ActiveUpdate servers and affected customers were initially advised to rollback to the previous version if possible.

Trend Micro released a new TMASE pattern (version 27128.00) on ActiveUpdate which was reported to resolve the issue.

Trend Micro is doing a thorough root cause analysis to determine the initial cause of the issue and implement any improvements as necessary.