If the size of the Apexone and Apexone IES databases is causing issues with backup and taking up most of the space on the database server, the following steps can be taken to resolve the issue:

1. In metadata storage, increase the 'Maximum memory allocation' up to 8 GB.
2. In metadata storage, increase the 'Maximum metadata storage' up to 200 GB.
3. Perform a shrink DB on the 3rd day after making these changes.

By following these steps, the size of the Apexone and Apexone IES databases should remain within acceptable limits and backups should no longer be an issue.