Procedure

1. Go to Service Management → Product Instance.
2. Click Create Product Instance.
3. Select the Instance type and click Next.
4. Define your new Protection Manager by specifying the required information.
   1. Select an Instance Type.
      You can create the following Protection Managers. Each type has certain limitations based on if you have already created instances or connected existing solutions.

      Protection Manager	Associated App	Notes and Limitations
      Standard Endpoint Protection	Endpoint Security Operations	You can create up to five instances from Product Instance. Instances created by updating from pre-existing solutions do not count towards the limitation on created instances.
      Server & Workload Protection	Endpoint Security Operations	You can create up to five instances from Product Instance. Instances created by updating from pre-existing solutions do not count towards the limitation on created instances.
      Cloud Email and Collaboration Protection	Email and Collaboration Security Operations	You can only have one instance.
      Cloud Email Gateway Protection	Email and Collaboration Security Operations	You can only have one instance.

   2. Specify a unique Display name to identify the instance in the associate app.
   3. Select the Region for the geographic location of the data center that hosts data being sent from endpoints to Trend Micro.
   4. Specify a description of the instance.
5. Click Save.

For more information: https://docs.trendmicro.com/en-us/documentation/article/trend-vision-one-prodinstnewprodinsta