Please refer to the following article for more information:
Virus scanning recommendations for Enterprise computers that are running currently supported versions of Windows.
You may also refer to this Microsoft article for Windows Server platforms.

• Oracle database files (if Oracle is installed under /opt)
  ・/opt/oracle/.*\.dbf
  ・/opt/oracle/.*\.ctl
  ・/opt/oracle/.*\.log
• Evolution data files
• Thunderbird data files
• Encrypted files
• JAR files for Real-Time Scan
• Archive files for Real-Time Scan
• DTX files for Real-Time Scan
• WAR files
• Groupwise folders
• Selected Open Enterprise Server files
  ・/media/nss//._NETWARE
  ・/media/nss//._ADMIN

Refer to the Acronis article:
Acronis Backup & Recovery: Exclude Program Folders and Executables from Security Programs.

Refer to the Knowledgebase article:
Appian Enterprise slows down or hangs when installed with OfficeScan or ServerProtect.

• C:\Program Files\NCR APTRA\Activate Core Service\bin\NCR.APTRA.ActivateCoreSrv.exe
• C:\Program Files\NCR APTRA\Advance NDC\AANDC.exe
• C:\Program Files\NCR APTRA\Advance NDC\ApplicationCore.exe
• C:\Program Files\NCR APTRA\Advance NDC\APTRAUSERCDI.exe
• C:\Program Files\NCR APTRA\Advance NDC\CampaignImport.exe
• C:\Program Files\NCR APTRA\Advance NDC\CheckSum_Tool.exe
• C:\Program Files\NCR APTRA\Advance NDC\CommunicationLog.exe
• C:\Program Files\NCR APTRA\Advance NDC\FEH.exe
• C:\Program Files\NCR APTRA\Advance NDC\HideTB.exe
• C:\Program Files\NCR APTRA\Advance NDC\InitEJ.exe
• C:\Program Files\NCR APTRA\Advance NDC\makecab.exe
• C:\Program Files\NCR APTRA\Advance NDC\NCR.APTRA.AppLoader.exe
• C:\Program Files\NCR APTRA\Advance NDC\NCR.APTRA.NDC.Monitor.exe
• C:\Program Files\NCR APTRA\Advance NDC\NCR.APTRA.NDC.SST.Configuration.exe
• C:\Program Files\NCR APTRA\Advance NDC\NCR.APTRA.SWUpdateSrv_WindowsService.exe
• C:\Program Files\NCR APTRA\Advance NDC\NCRSilentDebug.exe
• C:\Program Files\NCR APTRA\Advance NDC\NDCReboot.exe
• C:\Program Files\NCR APTRA\Advance NDC\PromoteCP.exe
• C:\Program Files\NCR APTRA\Advance NDC\VPITCPIPCOMServer.exe
• C:\Program Files\NCR APTRA\Advance NDC\Pd\makecab.exe
• C:\Program Files\NCR APTRA\Aggregate Installer\AggSrv.exe
• C:\Program Files\NCR APTRA\Aggregate Installer\Setup.exe
• C:\Program Files\NCR APTRA\Exception Handling\NCRPRS.exe
• C:\Program Files\NCR APTRA\Exception Handling\ueh.exe
• C:\Program Files\NCR APTRA\Mode Switch\ulms.exe
• C:\Program Files\NCR APTRA\NCR Remote Agent\Connector\EAccessTest.exe
• C:\Program Files\NCR APTRA\NCR Remote Agent\Connector\EAuthHelper.exe
• C:\Program Files\NCR APTRA\NCR Remote Agent\Connector\EKernel.exe
• C:\Program Files\NCR APTRA\NCR Remote Agent\Connector\EKernelEx.exe
• C:\Program Files\NCR APTRA\NCR Remote Agent\Connector\ELoader.exe
• C:\Program Files\NCR APTRA\NCR Remote Agent\Connector\EPACEval.exe
• C:\Program Files\NCR APTRA\NCR Remote Agent\Connector\EPwManager.exe
• C:\Program Files\NCR APTRA\NCR Remote Agent\Connector\ERemoteServer.exe
• C:\Program Files\NCR APTRA\NCR Remote Agent\Connector\ERemoteViewer.exe
• C:\Program Files\NCR APTRA\NCR Remote Agent\Connector\EShutdown.exe
• C:\Program Files\NCR APTRA\NCR Remote Agent\Connector\openssl.exe
• C:\Program Files\NCR APTRA\NCR Remote Agent\Connector\PingServer.exe
• C:\Program Files\NCR APTRA\NCR Remote Agent\Connector\SignDUConfig.exe
• C:\Program Files\NCR APTRA\NCR Remote Agent\Connector\xWatchDog.exe
• C:\Program Files\NCR APTRA\NCR Remote Agent\Desktop\Server\AxedaDesktopACL.exe
• C:\Program Files\NCR APTRA\NCR Remote Agent\Desktop\Server\AxedaDesktopServer.exe
• C:\Program Files\NCR APTRA\NCR Remote Agent\Desktop\Server\Driver\vista\setupdrv.exe
• C:\Program Files\NCR APTRA\NCR Remote Agent\Desktop\Server\Driver\vista64\setupdrv.exe
• C:\Program Files\NCR APTRA\NCR Remote Agent\Desktop\Server\Driver\w2K\setupdrv.exe
• C:\Program Files\NCR APTRA\NCR Remote Agent\Desktop\Server\Driver\xp\setupdrv.exe
• C:\Program Files\NCR APTRA\NCR Remote Agent\Desktop\Server\Driver\xp64\setupdrv.exe
• C:\Program Files\NCR APTRA\PcQwertyKeyboard\fmqwerty.exe
• C:\Program Files\NCR APTRA\PcSound\SndSync.exe
• C:\Program Files\NCR APTRA\Problem Determination Collection\EXTRACT.exe
• C:\Program Files\NCR APTRA\Problem Determination Collection\makecab.exe
• C:\Program Files\NCR APTRA\Resource Manager\aptraResourceManager.exe
• C:\Program Files\NCR APTRA\RS232IMCRW\croseexe.exe
• C:\Program Files\NCR APTRA\RS232IMCRW\fmimcrw.exe
• C:\Program Files\NCR APTRA\RS232IMCRW\imcrwldr.exe
• C:\Program Files\NCR APTRA\RS232IMCRW\ncrimcrw.exe
• C:\Program Files\NCR APTRA\Security Policies\Tools\infconv.exe
• C:\Program Files\NCR APTRA\Serial Detector\SerialDeviceDetector.exe
• C:\Program Files\NCR APTRA\SM Primitives\aptraSMPrimitives.exe
• C:\Program Files\NCR APTRA\SM Primitives\SSTManage.exe
• C:\Program Files\NCR APTRA\SSS Runtime Core\EXTRACT.exe
• C:\Program Files\NCR APTRA\SSS Runtime Core\uladminproxy.exe
• C:\Program Files\NCR APTRA\SSS Runtime Core\ulkbemul.exe
• C:\Program Files\NCR APTRA\SSS Runtime Core\ulloader.exe
• C:\Program Files\NCR APTRA\SSS Runtime Core\ulmasth.exe
• C:\Program Files\NCR APTRA\SSS Runtime Core\ulmntapp.exe
• C:\Program Files\NCR APTRA\SSS Runtime Core\ulpnpsync.exe
• C:\Program Files\NCR APTRA\SSS Runtime Core\ulrmpu.exe
• C:\Program Files\NCR APTRA\SSS Runtime Core\ulroot.exe
• C:\Program Files\NCR APTRA\SSS Runtime Core\ulsm.exe
• C:\Program Files\NCR APTRA\SSS Runtime Core\ulstart.exe
• C:\Program Files\NCR APTRA\SSS Runtime Core\ulSysApp.exe
• C:\Program Files\NCR APTRA\SSS Runtime Core\ultail.exe
• C:\Program Files\NCR APTRA\SSS Runtime Core\ulwait.exe
• C:\Program Files\NCR APTRA\SSS Runtime Core\WindowsXP-KB969238-x86-ENU.exe
• C:\Program Files\NCR APTRA\Tools\UA Log Collector\bin\NCR.APTRA.UALogCollector.exe
• C:\Program Files\NCR APTRA\Unified Agent\SNMP\bin\NCR.APTRA.CollectorProxySNMP.exe
• C:\Program Files\NCR APTRA\Unified Agent\WS\bin\NCR.APTRA.CollectorProxyWS.exe
• C:\Program Files\NCR APTRA\Unified Agent\WS\bin\NCR.APTRA.UAWSTSSrv.exe
• C:\Program Files\NCR APTRA\UOPS\UOPServer\kick.exe
• C:\Program Files\NCR APTRA\UOPS\UOPServer\UOPCOMServer.exe
• C:\Program Files\NCR APTRA\UOPS\UOPServer\UOPLoader.exe
• C:\Program Files\NCR APTRA\UOPS\UOPServer\UOPServer.exe
• C:\Program Files\NCR APTRA\USB Encrypting PIN Pad 2\USBEPP2Ldr.exe
• C:\Program Files\NCR APTRA\USB Loader Service\UsbLoaderSrv.exe
• C:\Program Files\NCR APTRA\USB Mini Miscellaneous Interface\UMMCLDR.exe
• C:\Program Files\NCR APTRA\USB Miscellaneous Interface\heartbeat.exe
• C:\Program Files\NCR APTRA\USB Miscellaneous Interface\WDOG_Uninstall.exe
• C:\Program Files\NCR APTRA\Usb80mmThermalPrinters\InstallationFiles\WinMsgMonitor.exe
• C:\Program Files\NCR APTRA\USBAcousticWaveTouchScreen\ELOConfigNCR.exe
• C:\Program Files\NCR APTRA\USBAcousticWaveTouchScreen\NCRSleep.exe
• C:\Program Files\NCR APTRA\USBAcousticWaveTouchScreen\ELODrivers\Setup.exe
• C:\Program Files\NCR APTRA\USBAcousticWaveTouchScreen\ELODrivers\32bit\AprPerfAdjustTool.exe
• C:\Program Files\NCR APTRA\USBAcousticWaveTouchScreen\ELODrivers\32bit\EloAprAutoCal.exe
• C:\Program Files\NCR APTRA\USBAcousticWaveTouchScreen\ELODrivers\32bit\EloAprConf.exe
• C:\Program Files\NCR APTRA\USBAcousticWaveTouchScreen\ELODrivers\32bit\EloDkMon.exe
• C:\Program Files\NCR APTRA\USBAcousticWaveTouchScreen\ELODrivers\32bit\EloDriverDefaults.exe
• C:\Program Files\NCR APTRA\USBAcousticWaveTouchScreen\ELODrivers\32bit\EloIrUTR.exe
• C:\Program Files\NCR APTRA\USBAcousticWaveTouchScreen\ELODrivers\32bit\EloMultiDrawXP.exe
• C:\Program Files\NCR APTRA\USBAcousticWaveTouchScreen\ELODrivers\32bit\EloRtBtn.exe
• C:\Program Files\NCR APTRA\USBAcousticWaveTouchScreen\ELODrivers\32bit\EloSelectComPort.exe
• C:\Program Files\NCR APTRA\USBAcousticWaveTouchScreen\ELODrivers\32bit\EloSetCal.exe
• C:\Program Files\NCR APTRA\USBAcousticWaveTouchScreen\ELODrivers\32bit\EloSetup.exe
• C:\Program Files\NCR APTRA\USBAcousticWaveTouchScreen\ELODrivers\32bit\EloTouchZones.exe
• C:\Program Files\NCR APTRA\USBAcousticWaveTouchScreen\ELODrivers\32bit\EloTTray.exe
• C:\Program Files\NCR APTRA\USBAcousticWaveTouchScreen\ELODrivers\32bit\EloVa.exe
• C:\Program Files\NCR APTRA\USBAcousticWaveTouchScreen\ELODrivers\32bit\EloVa25p.exe
• C:\Program Files\NCR APTRA\USBAcousticWaveTouchScreen\ELODrivers\32bit\FlashMon.exe
• C:\Program Files\NCR APTRA\USBAcousticWaveTouchScreen\ELODrivers\64bit\AprPerfAdjustTool.exe
• C:\Program Files\NCR APTRA\USBAcousticWaveTouchScreen\ELODrivers\64bit\EloAprConf.exe
• C:\Program Files\NCR APTRA\USBAcousticWaveTouchScreen\ELODrivers\64bit\EloDkMon.exe
• C:\Program Files\NCR APTRA\USBAcousticWaveTouchScreen\ELODrivers\64bit\EloDriverDefaults.exe
• C:\Program Files\NCR APTRA\USBAcousticWaveTouchScreen\ELODrivers\64bit\EloIrUTR.exe
• C:\Program Files\NCR APTRA\USBAcousticWaveTouchScreen\ELODrivers\64bit\EloMultiDrawXP.exe
• C:\Program Files\NCR APTRA\USBAcousticWaveTouchScreen\ELODrivers\64bit\EloRtBtn.exe
• C:\Program Files\NCR APTRA\USBAcousticWaveTouchScreen\ELODrivers\64bit\EloSelectComPort.exe
• C:\Program Files\NCR APTRA\USBAcousticWaveTouchScreen\ELODrivers\64bit\EloSetCal.exe
• C:\Program Files\NCR APTRA\USBAcousticWaveTouchScreen\ELODrivers\64bit\EloSetup.exe
• C:\Program Files\NCR APTRA\USBAcousticWaveTouchScreen\ELODrivers\64bit\EloTouchZones.exe
• C:\Program Files\NCR APTRA\USBAcousticWaveTouchScreen\ELODrivers\64bit\EloTTray.exe
• C:\Program Files\NCR APTRA\USBAcousticWaveTouchScreen\ELODrivers\64bit\EloVa.exe
• C:\Program Files\NCR APTRA\USBAcousticWaveTouchScreen\ELODrivers\64bit\EloVa25p.exe
• C:\Program Files\NCR APTRA\USBAcousticWaveTouchScreen\ELODrivers\64bit\FlashMon.exe
• C:\Program Files\NCR APTRA\USBAntiSkimmingModule\LdrSync.exe
• C:\Program Files\NCR APTRA\USBAntiSkimmingModule\SoDRcvry.exe
• C:\Program Files\NCR APTRA\USBAntiSkimmingModule\Support.exe
• C:\Program Files\NCR APTRA\USBAntiSkimmingModule\UASMLDR.exe
• C:\Program Files\NCR APTRA\USBAntiSkimmingModule\AppFirmware\Loader.exe
• C:\Program Files\NCR APTRA\USBAntiSkimmingModule\AppFirmware\Rcvry32.exe
• C:\Program Files\NCR APTRA\USBAntiSkimmingModule\AppFirmware\Rcvry64.exe
• C:\Program Files\NCR APTRA\USBGop\PMFiles\Setup.exe
• C:\Program Files\NCR APTRA\USBGop\PMFiles\Driver\install.exe
• C:\Program Files\NCR APTRA\USBGop\PMFiles\Utility\DMCCtrl.exe
• C:\Program Files\NCR APTRA\USBGop\PMFiles\Utility\PMonitor.exe
• C:\Program Files\NCR APTRA\USBGop\PMFiles\Utility\RButton.exe
• C:\Program Files\NCR APTRA\USBGop\TSFiles\setup-x86.exe
• C:\Program Files\NCR APTRA\USBGop\TSFiles\setup.exe
• C:\Program Files\NCR APTRA\USBGop\TSFiles\Common\HTrayApp.exe
• C:\Program Files\NCR APTRA\USBGop\TSFiles\Common\hwincal.exe
• C:\Program Files\NCR APTRA\USBGop\TSFiles\Common\tsun.exe
• C:\Program Files\NCR APTRA\USBGop\TSFiles\USB\NcrHTSE.exe
• C:\Program Files\NCR APTRA\USBTouchScreen\deinst.exe
• C:\Program Files\NCR APTRA\USBTouchScreen\SETUP.exe
• C:\Program Files\NCR APTRA\WMIDProv\CompileMOFs.exe
• C:\Program Files\NCR APTRA\WMIDProv\NCRDevProvSupport.exe
• C:\Program Files\NCR APTRA\XFS VDM Service Provider\VDAController.exe

• C:\Program Files (x86)\ArcGIS\Desktop10.6\bin\AdjustFrameCamera.exe
• C:\Program Files (x86)\ArcGIS\Desktop10.6\bin\AdjustRPC.exe
• C:\Program Files (x86)\ArcGIS\Desktop10.6\bin\ARConfig.exe
• C:\Program Files (x86)\ArcGIS\Desktop10.6\bin\ArcReaderHost.exe
• C:\Program Files (x86)\ArcGIS\Desktop10.6\bin\ArcSOMP.exe
• C:\Program Files (x86)\ArcGIS\Desktop10.6\bin\ComputeFTP.exe
• C:\Program Files (x86)\ArcGIS\Desktop10.6\bin\FilterDSM.exe
• C:\Program Files (x86)\ArcGIS\Desktop10.6\bin\FuseDSM.exe
• C:\Program Files (x86)\ArcGIS\Desktop10.6\bin\GenerateDSM.exe
• C:\Program Files (x86)\ArcGIS\Desktop10.6\bin\JavaConfigTool.exe
• C:\Program Files (x86)\ArcGIS\Desktop10.6\bin\RuntimeLocalServer.exe
• C:\Program Files (x86)\ArcGIS\Desktop10.6\bin\SetBingKey.exe
• C:\Program Files (x86)\ArcGIS\Desktop10.6\bin\TextureCookerService.exe
• C:\Program Files (x86)\ArcGIS\Desktop10.6\bin\ArcSOCP.exe
• C:\Program Files (x86)\ArcGIS\Desktop10.6\bin\BAEngine.exe
• C:\Program Files (x86)\ArcGIS\Desktop10.6\bin\aisdtsr2g.exe
• C:\Program Files (x86)\ArcGIS\Desktop10.6\bin\AppESRIPrintLocal.exe
• C:\Program Files (x86)\ArcGIS\Desktop10.6\bin\ArcScene.exe
• C:\Program Files (x86)\ArcGIS\Desktop10.6\bin\DesktopThumbnailUpdatingService.exe
• C:\Program Files (x86)\ArcGIS\Desktop10.6\bin\mp.exe
• C:\Program Files (x86)\ArcGIS\Desktop10.6\bin\SchematicDatasetEditor.exe
• C:\Program Files (x86)\ArcGIS\Desktop10.6\bin\aisdtslist.exe
• C:\Program Files (x86)\ArcGIS\Desktop10.6\bin\aisdtsp2a.exe
• C:\Program Files (x86)\ArcGIS\Desktop10.6\bin\AppROT.exe
• C:\Program Files (x86)\ArcGIS\Desktop10.6\bin\ArcCatalog.exe
• C:\Program Files (x86)\ArcGIS\Desktop10.6\bin\ArcGlobe.exe
• C:\Program Files (x86)\ArcGIS\Desktop10.6\bin\ArcMap.exe
• C:\Program Files (x86)\ArcGIS\Desktop10.6\bin\Categories.exe
• C:\Program Files (x86)\ArcGIS\Desktop10.6\bin\DesktopIndexingService.exe
• C:\Program Files (x86)\ArcGIS\Desktop10.6\bin\import71.exe
• C:\Program Files (x86)\ArcGIS\Desktop10.6\Utilities\AdvancedArcMapSettings.exe
• C:\Program Files (x86)\ArcGIS\Desktop10.6\Tools\DocDefragmenter.exe
• C:\Program Files (x86)\ArcGIS\Desktop10.6\Tools\MXDDoctor.exe
• C:\Program Files (x86)\ArcGIS\Desktop10.6\bin\MakeServerStyleSet.exe
• C:\Program Files (x86)\ArcGIS\Desktop10.6\java\jre\bin\jabswitch.exe
• C:\Program Files (x86)\ArcGIS\Desktop10.6\java\jre\bin\java.exe
• C:\Program Files (x86)\ArcGIS\Desktop10.6\java\jre\bin\javacpl.exe
• C:\Program Files (x86)\ArcGIS\Desktop10.6\java\jre\bin\java-rmi.exe
• C:\Program Files (x86)\ArcGIS\Desktop10.6\java\jre\bin\javaw.exe
• C:\Program Files (x86)\ArcGIS\Desktop10.6\java\jre\bin\javaws.exe
• C:\Program Files (x86)\ArcGIS\Desktop10.6\java\jre\bin\jjs.exe
• C:\Program Files (x86)\ArcGIS\Desktop10.6\java\jre\bin\jp2launcher.exe
• C:\Program Files (x86)\ArcGIS\Desktop10.6\java\jre\bin\keytool.exe
• C:\Program Files (x86)\ArcGIS\Desktop10.6\java\jre\bin\kinit.exe
• C:\Program Files (x86)\ArcGIS\Desktop10.6\java\jre\bin\klist.exe
• C:\Program Files (x86)\ArcGIS\Desktop10.6\java\jre\bin\ktab.exe
• C:\Program Files (x86)\ArcGIS\Desktop10.6\java\jre\bin\orbd.exe
• C:\Program Files (x86)\ArcGIS\Desktop10.6\java\jre\bin\pack200.exe
• C:\Program Files (x86)\ArcGIS\Desktop10.6\java\jre\bin\policytool.exe
• C:\Program Files (x86)\ArcGIS\Desktop10.6\java\jre\bin\rmid.exe
• C:\Program Files (x86)\ArcGIS\Desktop10.6\java\jre\bin\rmiregistry.exe
• C:\Program Files (x86)\ArcGIS\Desktop10.6\java\jre\bin\servertool.exe
• C:\Program Files (x86)\ArcGIS\Desktop10.6\java\jre\bin\ssvagent.exe
• C:\Program Files (x86)\ArcGIS\Desktop10.6\java\jre\bin\tnameserv.exe
• C:\Program Files (x86)\ArcGIS\Desktop10.6\java\jre\bin\unpack200.exe
• C:\Program Files (x86)\ArcGIS\Desktop10.6\bin\agfshp.exe
• C:\Program Files (x86)\ArcGIS\Desktop10.6\bin\avmifshp.exe
• C:\Program Files (x86)\ArcGIS\Desktop10.6\bin\SHAPEDXF.exe
• C:\Program Files (x86)\ArcGIS\Desktop10.6\bin\shpagf.exe
• C:\Program Files (x86)\ArcGIS\Desktop10.6\ArcToolbox\Scripts\TestGPRAM.exe

For more information, refer to the following ARCserver articles:

• Antivirus Process and Folder Exclusions for ARCserve Backup
• CA ARCserve RHA best practices with regards to Anti-virus exclusion
• How to exclude Arcserve RHA spool folder from the antivirus scans
• ARCserve D2D

• C:\Program Files\Autodesk\Inventor 2013\Bin\Inventor.exe
• C:\Program Files\Autodesk\Vault Professional 201\Explorer\Connectivity.VaultPro.exe
• C:\Program Files\Autodesk\AutoCAD 2013\acad.exe
• C:\Program Files\Autodesk\Inventor Fusion 2013\Inventor Fusion.exe
• C:\Program Files\Autodesk\DWG TrueView 2013\dwgviewr.exe
• C:\Program Files (x86)\Autodesk\Autodesk Design Review 2013\DesignReview.exe
• C:\Program Files\Autodesk\Product Design Suite 2013\Bin\ProductDesignSuite.exe

• C:\Program Files\Cisco\AMP\6.2.19\sfc.exe
• C:\Program Files\Cisco\AMP\6.2.19\uninstall.exe
• C:\Program Files\Cisco\AMP\clamav\0.100.2.63\freshclamwrap.exe
• C:\Program Files\Cisco\AMP\clamav\0.100.2.63\freshclam.exe
• C:\Program Files\Cisco\AMP\6.2.19\ipsupporttool.exe
• C:\Program Files\Cisco\AMP\6.2.19\ConnectivityTool.exe
• C:\Program Files\Cisco\AMP\6.2.19\creport.exe
• C:\Program Files\Cisco\AMP\6.2.19\iptray.exe
• C:\Program Files\Cisco\AMP\6.2.19\sfc.exe
• C:\Program Files\Cisco\AMP\6.2.19\updater.exe

• C:\Program Files (x86)\Cisco\Cisco HostScan\bin\cscan.exe
• C:\Program Files (x86)\Cisco\Cisco HostScan\bin\ciscod.exe
• C:\Program Files (x86)\Cisco\Cisco HostScan\bin\cstub.exe
• C:\Program Files (x86)\Cisco\Cisco AnyConnect Secure Mobility Client\vpnui.exe
• C:\Program Files (x86)\Cisco\Cisco AnyConnect Secure Mobility Client\vpndownloader.exe
• C:\Program Files (x86)\Cisco\Cisco AnyConnect VPN Client\vpndownloader.exe
• C:\Program Files (x86)\Cisco\Cisco AnyConnect Secure Mobility Client\vpncli.exe
• C:\Program Files (x86)\Cisco\Cisco AnyConnect Secure Mobility Client\vpnagent.exe
• C:\Program Files (x86)\Cisco\Cisco AnyConnect Secure Mobility Client\VACon64.exe
• C:\Program Files (x86)\Cisco\Cisco AnyConnect Secure Mobility Client\aciseuac.exe
• C:\Program Files (x86)\Cisco\Cisco AnyConnect Secure Mobility Client\aciseposture.exe
• C:\Program Files (x86)\Cisco\Cisco AnyConnect Secure Mobility Client\aciseagent.exe
• C:\Program Files (x86)\Cisco\Cisco AnyConnect Secure Mobility Client\acise.exe
• C:\Program Files (x86)\Cisco\Cisco HostScan\lib\wa_3rd_party_host_32.exe
• C:\Program Files (x86)\Cisco\Cisco HostScan\lib\wa_3rd_party_host_64.exe
• C:\Program Files (x86)\Cisco\Cisco AnyConnect Secure Mobility Client\opswat\wa_3rd_party_host_32.exe
• C:\Program Files (x86)\Cisco\Cisco AnyConnect Secure Mobility Client\opswat\wa_3rd_party_host_64.exe

• Drive:\Program Files (x86)\cisco\cisco anyconnect vpn client\vpnagent.exe
• Drive:\Program Files (x86)\cisco\cisco anyconnect vpn client\vpnui.exe

• C:\program files\citrix\ICA Client\reciver.exe
• C:\program files\citrix\ICA Client\pnamain.exe
• C:\program files\citrix\ICA Client\concentr.exe
• C:\program files\citrix\ICA Client\wfcrun32.exe
• C:\program files\citrix\ICA Client\PNagent.exe
• C:\program files\Citrix\Broker\Service\BrokerService.exe
• C:\program files\Citrix\Broker\Service\HighAvailabilityService.exe
• C:\program files\Citrix\ConfigSync\ConfigSyncService.exe
• C:\program files\Citrix\User Profile Manager\UserProfileManager.exe
• C:\program files\Citrix\Virtual Desktop Agent\BrokerAgent.exe
• C:\Windows\System32\spoolsv.exe
• C:\Windows\System32\winlogon.exe
• C:\program files\Citrix\ICAService\picaSvc2.exe
• C:\program files\Citrix\ICAService\CpSvc.exe
• C:\program files\Citrix\Provisioning Services\BNTFTP.exe
• C:\program files\Citrix\Provisioning Services\PVSTSB.exe
• C:\program files\Citrix\Provisioning Services\StreamService.exe
• C:\program files\Citrix\Provisioning Services\StreamProcess.exe
• C:\program files\Citrix\Provisioning Services\soapserver.exe
• C:\program files\Citrix\Provisioning Services\Inventory.exe
• C:\program files\Citrix\Provisioning Services\Notifier.exe
• C:\program files\Citrix\Provisioning Services\MgmntDaemon.exe
• C:\program files\Citrix\Provisioning Services\BNPXE.exe
• C:\program files\Citrix\XaXdCloudProxy\XaXdCloudProxy.exe

On Citrix systems, the following extensions have been causing performance problems.
Exclude these file extensions to avoid any performance problems:

• *.LOG, *.DAT, *.TMP, *.POL, *.PF.

• Citrix Guidelines for Antivirus Software Configuration
• Citrix Consolidated List of Antivirus Exclusions

• %SystemRoot%\System32\winlogon.exe

Refer to the following articles:

• Recommended Antivirus Exclusions for Windows
• Recommended Antivirus Exclusions for UNIX and Macintosh

• C:\Program Files (x86)\CyberSafe\bin\CSTBesigauth32.exe
• C:\Program Files (x86)\CyberSafe\bin\khostname.exe
• C:\Program Files (x86)\CyberSafe\bin\ktutil.exe
• C:\Program Files (x86)\CyberSafe\bin\getsite.exe
• C:\Program Files (x86)\CyberSafe\bin\CSTBpmem_cc32.exe
• C:\Program Files (x86)\CyberSafe\bin\CSTBcred32.exe

• C:\Program Files\DGAgent\Verity\miniIdol\IDOL\agentstoremini\agentstore.exe
• C:\Program Files\DGAgent\Verity\kv\_nti40\bin\tstxtract.exe
• C:\Program Files\DGAgent\Verity\kv\_nti40\bin\kvoop.exe
• C:\Program Files\DGAgent\Verity\kv\_nti40\bin\FilterTestDotNet.exe
• C:\Program Files\DGAgent\Verity\kv\_nti40\bin\filter.exe
• C:\Program Files\DGAgent\DgUpdate\DgUpdate.exe
• C:\Program Files\DGAgent\DGCipher.exe
• C:\Program Files\DGAgent\DG-Diag.exe
• C:\Program Files\DGAgent\iftest.exe
• C:\Program Files\DGAgent\dg_UsrEncrProvider.exe
• C:\Program Files\DGAgent\DgWip.exe
• C:\Program Files\DGAgent\DgUpdate.exe
• C:\Program Files\DGAgent\DgService.exe
• C:\Program Files\DGAgent\DgScan.exe
• C:\Program Files\DGAgent\DgProbe.exe
• C:\Program Files\DGAgent\DgPrompt.exe
• C:\Program Files\DGAgent\DGFolderScan.exe
• C:\Program Files\DGAgent\DgAgent.exe

The data directory is used to store Domino email messages.
Repeated scanning of this folder while it is being updated with new messages is not an efficient way to scan locally stored email.
Use virus scanning applications such as ScanMail for Domino to handle email viruses.

By default, the Domino data directory for a non-partitioned installation is:
\ Lotus \ Domino \ Data.

Refer to the following Microsoft articles:

• Exchange 2007: File-Level Antivirus Scanning on Exchange 2007
• Exchange 2010: File-Level Antivirus Scanning on Exchange 2010
• Exchange 2013: Anti-Virus Software in the Operating System on Exchange Servers
• Exchange 2016: Running Windows antivirus software on Exchange 2016 servers
• Office 2013 (including Office 365): Plan antivirus scanning for Outlook 2013

Refer to this Microsoft article:

• Review hardware and software requirements (FAST Search Server 2010 for SharePoint)

Add the following locations/files to the exclusion list:

• SERVER*.vhdx (File Server)
• [EXAMPLE.COM|http://example.com/]*.VHDX (DFS namespace)
• L:*.vhdx (Local drive on the file server)
• C:\Windows\TEMP*.vhdx
• C:\Program Files\FSLogix*

Refer to this KB article:

• Firewall setting configuration for Intel WiDi/Miracast in OfficeScan.

Refer to the following article:

• Recommended Anti-Virus and AppSense Exclusions.

• C:\Program Files (x86)\Laserfiche\Client\Scanning\WIAScanClient91.exe
• C:\Program Files (x86)\Laserfiche\Client\Scanning\LFScan.exe
• C:\Program Files (x86)\Laserfiche\Client\Scanning\LfTwainClient91.exe
• C:\Program Files (x86)\Laserfiche\Client\Scanning\ScanConnectClient91.exe
• C:\Program Files (x86)\Laserfiche\Client\Scanning\ThumbnailGen.exe
• C:\Program Files (x86)\Laserfiche\Client\Scanning\BPSessionClient91.exe
• C:\Program Files (x86)\Laserfiche\Client\Scanning\FileScanClient91.exe
• C:\Program Files (x86)\Laserfiche\Client\Scanning\LfKofaxClient91.exe
• C:\Program Files (x86)\Laserfiche\Client\LFOffice\Laserfiche.OfficeMonitor.exe
• C:\Program Files (x86)\Laserfiche\Client\LFOffice\Laserfiche.OfficePlugin.WebAccess.Monitor.exe

• C:\ProgramData\Lenovo\ImController\Plugins\LenovoBatteryGaugePackage\x64\RegAsm.exe
• C:\Program Files\Lenovo\HOTKEY\PerfModeSettings.exe
• C:\Program Files\Lenovo\HOTKEY\tposdc.exe
• C:\Program Files\Lenovo\HOTKEY\micmutes.exe
• C:\Program Files\Lenovo\HOTKEY\micmutec.exe
• C:\Program Files\Lenovo\HOTKEY\kbdmgr.exe
• C:\Program Files\Lenovo\HOTKEY\specialkeyhelper.exe
• C:\Program Files\Lenovo\HOTKEY\kbdmgrc.exe
• C:\Program Files\Lenovo\HOTKEY\setapps.exe
• C:\Program Files (x86)\Lenovo\System Update\unins000.exe
• C:\Program Files (x86)\Lenovo\System Update\tpisysidsu.exe
• C:\Program Files (x86)\Lenovo\System Update\EnumCD.exe
• C:\Program Files (x86)\Lenovo\System Update\mapdrv.exe
• C:\Program Files (x86)\Lenovo\System Update\clearsuservice.exe
• C:\Program Files (x86)\Lenovo\System Update\IsMetroMode.exe
• C:\Program Files (x86)\Lenovo\System Update\ApsChk86.exe
• C:\Program Files (x86)\Lenovo\System Update\ApsChk64.exe
• C:\Program Files (x86)\Lenovo\System Update\Installer64.exe
• C:\Program Files (x86)\Lenovo\System Update\DiDriverInstall64.exe
• C:\Program Files (x86)\Lenovo\System Update\egather\IA.exe
• C:\Program Files (x86)\Lenovo\System Update\uncsetting.exe
• C:\Program Files (x86)\Lenovo\System Update\tvsuShim.exe
• C:\Program Files (x86)\Lenovo\System Update\tvsu.exe
• C:\Program Files (x86)\Lenovo\System Update\susetsched.exe
• C:\Program Files (x86)\Lenovo\System Update\UNCServer.exe
• C:\Program Files (x86)\Lenovo\System Update\UACSdk.exe
• C:\Program Files (x86)\Lenovo\System Update\TvtBiosCheck.exe
• C:\Program Files (x86)\Lenovo\System Update\Tvsukernel.exe
• C:\Program Files (x86)\Lenovo\System Update\TvsuCommandLauncher.exe
• C:\Program Files (x86)\Lenovo\System Update\StartSuService.exe
• C:\Program Files (x86)\Lenovo\System Update\SUService.exe
• C:\Program Files (x86)\Lenovo\System Update\ConfigService.exe
• C:\Program Files (x86)\Lenovo\System Update\ConfigScheduledTask.exe
• C:\Program Files (x86)\Lenovo\System Update\7za.exe

This option is best disabled.
If it is enabled, it may create unnecessary network traffic when the end users access remote paths or mapped network drives.
It can severely impact the user’s experience.
Consider disabling this function if all workstations have OfficeScan client installed and are updated to the latest virus signature.

Please refer to the following McAfee article for detailed instructions:

• Endpoint Security and VirusScan Enterprise exclusions for Data Loss Prevention Endpoint to improve performance.

Process exclusions for AD DS and AD DS-related support files:

• %systemroot%\System32\ntfrs.exe
• %systemroot%\System32\lsass.exe

• Virus scanning recommendations for Enterprise computers that are running currently supported versions of Windows.

• C:\Program Files (x86)\Microsoft Azure Information Protection\MSIP.Scanner.exe
• C:\Program Files (x86)\Microsoft Azure Information Protection\MSIP.exe
• cutionHost32.exe
• C:\Program Files (x86)\Microsoft Azure Information Protection\MSIP.App.exe
• C:\Program Files (x86)\Microsoft Azure Information Protection\MSIP.exe
• cutionHost.exe
• C:\Program Files (x86)\Microsoft Azure Information Protection\MSIP.Tools.Configuration.exe
• C:\Program Files (x86)\Microsoft Azure Information Protection\MSIP.Viewer.exe
• C:\Program Files (x86)\Microsoft Azure Information Protection\adxregistrator.exe

• Recommended antivirus exclusions for Hyper-V hosts
• Running Windows antivirus software on Exchange servers
• Configure Windows Defender Antivirus exclusions on Windows Server
• How to choose antivirus software to run on computers that are running SQL Server
• Antivirus software that is not cluster-aware may cause problems with Cluster Services
• Recommended antivirus exclusions for System Center Virtual Machine Manager and managed hosts
• Virus scanning recommendations for Enterprise computers that are running currently supported versions of Windows

Exclude the directory or partition where MS Exchange stores its mailbox.
Use virus scanning applications like ScanMail for Exchange to handle email viruses.
Installable File System (IFS) drive M must also be excluded to prevent the corruption of the Exchange Information Store.

Refer to this article:

• Recommended antivirus exclusions for Hyper-V hosts.

• C:\Windows\System32\Vmms.exe
• C:\Windows\System32\Vmwp.exe
• C:\Windows\System32\Vmsp.exe
• C:\Windows\System32\Vmcompute.exe
• C:\Windows\System32\dfsr.exe
• C:\Windows\System32\dfsrs.exe
• C:\Windows\system32\inetsrv\w3wp.exe
• C:\Windows\SysWOW64\inetsrv\w3wp.exe
• C:\PHP5433\php-cgi.exe

Web Server log files should be excluded from scanning.
By default, IIS logs are saved in:\inetpub\logs\*.log.

Scan exclusion guidelines for Microsoft Lync:

• Microsoft Lync 2010: Specifying Antivirus Scanning Exclusions
• Microsoft Lync 2013: Antivirus Scanning Exclusions for Lync Server 2013

Refer to this Microsoft article:

• Certain folders may have to be excluded from antivirus scanning when you use a file-level antivirus program in SharePoint.

Because scanning may hinder performance, large databases should not be scanned.
Since Microsoft SQL Server databases are dynamic, they exclude the directory and backup folders from the scan list.
If it is necessary to scan database files, a scheduled task can be created to scan them during off-peak hours.

Refer to the following article from Microsoft to obtain advised SQL server exclusion list:

• How to choose antivirus software to run on computers that are running SQL Server.

• C:\Aptra\USBDISPENSER\setup.exe
• C:\Aptra\USBDISPENSER\Comps\VisualC2.16d\010101.8c0\VC2015RT.exe
• C:\iSuite\iJournal\EJCutOff.exe
• C:\iSuite\iJournal\IJournalATM.exe
• C:\iSuite\iJournal\iJournalATMCutover.exe
• C:\iSuite\iJournal\InstallUtil.exe
• C:\iSuite\NCRAppManager\NCRAppManager.exe
• C:\iSuite\NCRAppManager\NCRAppManager.vshost.exe
• C:\iSuite Client\iJournalSetup_3.3.13_All banks Win 7.exe
• C:\iSuite Client\NCRAppManager_1.0.0.2.exe
• C:\iSuite Client\VCRuntime2005.exe
• C:\MSSOHAR_V1\hosts.exe
• C:\MSSOHAR_V1\PredictiveServicesCertificateUpdate.exe
• C:\MSSOHAR_V1\UAWS.exe
• C:\NCR\Fetch.exe
• C:\NCR\UAWS\setup.exe
• C:\Program Files\Common Files\NCR\MAKECAB.exe
• C:\Program Files\Common Files\NCR\NCRXFSInternalError.exe
• C:\Program Files\Common Files\NCR\PRSCheck.exe
• C:\Program Files\Common Files\NCR\StdWrap.exe
• C:\Program Files\Common Files\NCR\ulfm.exe
• C:\Program Files\Common Files\NCR\ulwait.exe
• C:\Program Files\Common Files\SafeNet Sentinel\Sentinel Security Runtime\sntlsrtsrvr.exe
• C:\Program Files\Common Files\SafeNet Sentinel\Sentinel System Driver\Drv32InstLauncher.exe
• C:\Program Files\Common Files\SafeNet Sentinel\Sentinel System Driver\RemoveDriverTrail.exe
• C:\Program Files\Common Files\SafeNet Sentinel\Sentinel System Driver\RemoveDriverTrailLauncher.exe
• C:\Program Files\Common Files\SafeNet Sentinel\Sentinel System Driver\SentinelDrv32Support.exe
• C:\Program Files\Common Files\SafeNet Sentinel\Sentinel System Driver\SetupSysDriver.exe
• C:\Program Files\Elo Touch Solutions\AprPerfAdjustTool.exe
• C:\Program Files\Elo Touch Solutions\EloAprAutoCal.exe
• C:\Program Files\Elo Touch Solutions\EloAprConf.exe
• C:\Program Files\Elo Touch Solutions\EloDkMon.exe
• C:\Program Files\Elo Touch Solutions\EloDriverDefaults.exe
• C:\Program Files\Elo Touch Solutions\EloIrUTR.exe
• C:\Program Files\Elo Touch Solutions\EloMultiDrawXP.exe
• C:\Program Files\Elo Touch Solutions\EloRtBtn.exe
• C:\Program Files\Elo Touch Solutions\EloSelectComPort.exe
• C:\Program Files\Elo Touch Solutions\EloSetCal.exe
• C:\Program Files\Elo Touch Solutions\EloSetup.exe
• C:\Program Files\Elo Touch Solutions\EloTouchZones.exe
• C:\Program Files\Elo Touch Solutions\EloTTray.exe
• C:\Program Files\Elo Touch Solutions\EloVa.exe
• C:\Program Files\Elo Touch Solutions\EloVa25p.exe
• C:\Program Files\Elo Touch Solutions\FlashMon.exe
• C:\Windows\NCR\Autologon.exe
• C:\Windows\NCR\DosHide.exe
• C:\Windows\NCR\DosSee.exe
• C:\Windows\NCR\HTaskbar.exe
• C:\Windows\NCR\NoCursor.exe
• C:\Windows\NCR\PROCESS.exe
• C:\Windows\NCR\StartUp.exe
• C:\Windows\NCR\STaskbar.exe
• C:\Windows\NCR\ULSETPRS.exe
• C:\Windows\NCR\ULSHUTD.exe
• C:\Windows\NCR\ULSLEEP.exe
• C:\Windows\NCR\USBPRT.exe
• C:\Windows\NCR\vidchng.exe
• C:\Windows\NCR\Tools\Dev2Csv.exe
• C:\Windows\NCR\Tools\Fetch.exe
• C:\Windows\NCR\Tools\GBNAInfo.exe
• C:\Windows\NCR\Tools\reg.exe
• C:\Windows\NCR\Tools\SaveBVInfo.exe
• C:\Windows\NCR\Tools\Shakari.exe
• C:\Windows\NCR\Tools\Tallies.exe
• C:\Windows\NCR\Tools\zip.exe
• C:\Windows\Panther\setup.exe

• .dbf - Database file
• .log - Online Redo Log
• .rdo - Online Redo Log
• .arc - Archive log
• .ctl - Control files

• %Program Files%\Palo Alto Networks\Traps\
• %ProgramData%\Cyvera\
• Cyserver.exe
• CyveraConsole.exe
• CyveraService.exe
• tlaworker.exe

• SAP ABAP or Java installs: \usr\sap\
• SAP Content Server Install: \SAPDB\
• SAP Printer Server: SAPSprint.exe
• Servers where are SAPGui is installed: lsagent.exe
• C:\Program Files (x86)\SAP\FrontEnd\SAPgui\saplgpad.exe
• C:\Program Files (x86)\SAP\NWBC65\cef\CefSharp.BrowserSubprocess.exe
• C:\Program Files (x86)\SAP\NWBC65\NwbcUrlHandler.exe
• C:\Program Files (x86)\SAP\NWBC65\NwbcTaskbarHandler.exe
• C:\Program Files (x86)\SAP\NWBC65\NwbcPropertyCollector.exe
• C:\Program Files (x86)\SAP\NWBC65\NwbcDesktopAgent.exe
• C:\Program Files (x86)\SAP\NWBC65\NwbcCore.exe
• C:\Program Files (x86)\SAP\NWBC65\NwbcBrowserHost.exe
• C:\Program Files (x86)\SAP\NWBC65\NWBC.exe
• C:\Program Files (x86)\SAP\FrontEnd\SAPgui\visu_se.exe
• C:\Program Files (x86)\SAP\FrontEnd\SAPgui\visualiz.exe
• C:\Program Files (x86)\SAP\FrontEnd\SAPgui\ssfrfc.exe
• C:\Program Files (x86)\SAP\FrontEnd\SAPgui\sapsettingsshow.exe
• C:\Program Files (x86)\SAP\FrontEnd\SAPgui\sapshcut.exe
• C:\Program Files (x86)\SAP\FrontEnd\SAPgui\SAPhttp.exe
• C:\Program Files (x86)\SAP\FrontEnd\SAPgui\SapGuiServer.exe
• C:\Program Files (x86)\SAP\FrontEnd\SAPgui\SAPgui.exe
• C:\Program Files (x86)\SAP\FrontEnd\SAPgui\SAPftp.exe
• C:\Program Files (x86)\SAP\FrontEnd\SAPgui\sapcms.exe
• C:\Program Files (x86)\SAP\FrontEnd\SAPgui\niping.exe
• C:\Program Files (x86)\SAP\FrontEnd\SAPgui\omsprint.exe
• C:\Program Files (x86)\SAP\FrontEnd\SAPgui\gnxlx.exe
• C:\Program Files (x86)\SAP\FrontEnd\SAPgui\gnupx.exe
• C:\Program Files (x86)\SAP\FrontEnd\SAPgui\gnwdx.exe
• C:\Program Files (x86)\SAP\FrontEnd\SAPgui\gnstx.exe
• C:\Program Files (x86)\SAP\FrontEnd\SAPgui\gnsux.exe
• C:\Program Files (x86)\SAP\FrontEnd\SAPgui\gnpox.exe
• C:\Program Files (x86)\SAP\FrontEnd\SAPgui\gnscx.exe
• C:\Program Files (x86)\SAP\FrontEnd\SAPgui\gnmsx.exe
• C:\Program Files (x86)\SAP\FrontEnd\SAPgui\gnnex.exe
• C:\Program Files (x86)\SAP\FrontEnd\SAPgui\gnhix.exe
• C:\Program Files (x86)\SAP\FrontEnd\SAPgui\gnhox.exe
• C:\Program Files (x86)\SAP\FrontEnd\SAPgui\gnhpx.exe
• C:\Program Files (x86)\SAP\FrontEnd\SAPgui\gngax.exe
• C:\Program Files (x86)\SAP\FrontEnd\SAPgui\gnetx.exe
• C:\Program Files (x86)\SAP\FrontEnd\SAPgui\gneux.exe
• C:\Program Files (x86)\SAP\FrontEnd\SAPgui\gnbux.exe
• C:\Program Files (x86)\SAP\FrontEnd\SAPgui\gndlx.exe
• C:\Program Files (x86)\SAP\FrontEnd\SAPgui\gnbax.exe
• C:\Program Files (x86)\SAP\FrontEnd\SAPgui\gnbmx.exe
• C:\Program Files (x86)\SAP\FrontEnd\SAPgui\SAPGUIControlPlugin.exe
• C:\Program Files (x86)\SAP\FrontEnd\SAPgui\FrontOptEdit.exe
• C:\Program Files (x86)\SAP\FrontEnd\SAPgui\Unicode\SAPhttp.exe
• C:\Program Files (x86)\SAP\FrontEnd\SAPgui\Unicode\SAPftp.exe
• C:\Program Files (x86)\SAP\SapSetup\Setup\SapStart.exe
• C:\Program Files (x86)\SAP\FrontEnd\SAPgui\guixt.exe
• C:\Program Files (x86)\SAP\Business Explorer\BI\BExWebApplicationDesigner.exe
• C:\Program Files (x86)\SAP\Business Explorer\BI\BExReportDesignerStarter.exe
• C:\Program Files (x86)\SAP\Business Explorer\BI\BExQueryDesignerStarter.exe
• C:\Program Files (x86)\SAP\Business Explorer\BI\BExInstaller.exe
• C:\Program Files (x86)\SAP\Business Explorer\BI\BExAnalyzer.exe
• C:\Program Files (x86)\SAP\SapSetup\Setup\SapRegSv.exe
• C:\Program Files (x86)\SAP\SapSetup\Setup\NwSnapshot64.exe
• C:\Program Files (x86)\SAP\SapSetup\Setup\NwSAPSetupOnRebootInstSvc.exe
• C:\Program Files (x86)\SAP\SapSetup\Setup\DotNetUtils20.exe
• C:\Program Files (x86)\SAP\SapSetup\Setup\DotNetUtils40.exe
• C:\Program Files (x86)\SAP\SapSetup\Setup\NwSapSetup.exe
• C:\Program Files (x86)\SAP\SapSetup\Setup\NwCheckWorkstation.exe
• C:\Program Files (x86)\SAP\SapSetup\OnRebootSvc\sapregsv.exe
• C:\Program Files (x86)\SAP\SapSetup\OnRebootSvc\NwSnapshot64.exe
• C:\Program Files (x86)\SAP\SapSetup\OnRebootSvc\NWSAPSetupOnRebootInstSvc.exe
• C:\Program Files (x86)\SAP\SapSetup\OnRebootSvc\DotNetUtils20.exe
• C:\Program Files (x86)\SAP\SapSetup\OnRebootSvc\DotNetUtils40.exe
• C:\Program Files (x86)\SAP\FrontEnd\SAPgui\help_04.exe
• C:\Program Files (x86)\SAP\FrontEnd\SAPgui\htmlhelp\shh.exe
• C:\Program Files (x86)\SAP\FrontEnd\SAPgui\Testtools\Check_DOI.exe

Refer to the Knowledgebase article:

• Excluding third-party software from the OfficeScan Realtime Scan.

• ~\Symantec\Backup Exec\beremote.exe
• ~\Symantec\Backup Exec\beserver.exe
• ~\Symantec\Backup Exec\bengine.exe
• ~\Symantec\Backup Exec\benetns.exe
• ~\Symantec\Backup Exec\pvlsvr.exe
• ~\Symantec\Backup Exec\BkUpexec.exe

• Boot image: C:\Windows\TEMP\BootImages\
• OS image: \ConfigMgr_OfflineImageServicing and subfolders.\

• %allusersprofile%\NTUser.pol
• %systemroot%\system32\GroupPolicy\registry.pol
• %windir%\Security\database\*.chk
• %windir%\Security\database\*.edb
• %windir%\Security\database\*.jrs
• %windir%\Security\database\*.log
• %windir%\Security\database\*.sdb
• %windir%\SoftwareDistribution\Datastore\Datastore.edb
• %windir%\SoftwareDistribution\Datastore\Logs\edb.chk
• %windir%\SoftwareDistribution\Datastore\Logs\edb*.log
• %windir%\SoftwareDistribution\Datastore\Logs\Edbres00001.jrs
• %windir%\SoftwareDistribution\Datastore\Logs\Edbres00002.jrs
• %windir%\SoftwareDistribution\Datastore\Logs\Res1.log
• %windir%\SoftwareDistribution\Datastore\Logs\Res2.log
• %windir%\SoftwareDistribution\Datastore\Logs\tmp.edb
• %programfiles%\Microsoft Configuration Manager\Inboxes\*.*
• %programfiles(x86)%\Microsoft Configuration Manager\Inboxes\*.*

• For Operations Manager 2007 or Operations Manager 2007 R2:
  C:\Program Files\System Center Operations Manager\Health Service State
   
  The placeholder represents "2007" for Operations Manager 2007 or Operations Manager 2007 R2.
• For Operations Manager 2012:
  C:\Program Files\System Center Operations Manager\\Health Service State
   
  The placeholder represents "Agent" or "Server" for Operations Manager
• For Operations Manager 2012 R2 (management server):
  C:\Program Files\Microsoft System Center 2012 R2\Operations Manager\Server\Health Service State
• For Operations Manager 2012 R2 (gateway server):
  C:\Program Files\System Center Operations Manager\Gateway\Health Service State
• For Operations Manager 2012 R2 (agent):
  C:\Program Files\Microsoft Monitoring Agent\Agent\Health Service State

• SQL database servers:
  These exclusions include the SQL Server database files that are used by Operations Manager components and the system database files for the master database and for the tempdb database.For example:
  ・MDF
  ・LDF
   
• Operations Manager (management servers, gateways, and agents):
  These exclusions include the queue and log files that are used by Operations Manager. For Example:
  ・EDB
  ・CHK
  ・LOG

• *CVD.exe
• *Cvfwd.exe
• *ClMgrS.exe
• *GxSearchServer
• *tomcat.exe
• *EvMgrS.exe
• *AppMgrSvc.exe
• *JobMgr.exe
• *MediaManager.exe
• *QSDK.exe
• *CVMountd.exe
• *CVContentPreview.exe
• *CVMessageQueue.exe
• *ClMgrS.exe
• *CVRepSvc.exe
• *VSS_SWProv_Svc.exe
• *VSS_HWPROV.SCV.exe
• *CVJavaWorkflow(Instance001).exe
• *Tomcat.exe
• *GxWinClusPlugin.exe

Refer to this Veeam article:

• How to configure antivirus exclusions to prevent interaction with Veeam Backup & Replication.

• C:\Program Files\VMware\VMware View\Agent\bin\VMWVvpsvc.exe
• C:\PROGRAM FILES\VMWARE\VMWARE TOOLS\VMTOOLSD.exe
• C:\Program Files\Common Files\VMware\View Composer Guest Agent\vmware-svi-ga.exe
• C:\Program Files\VMware\VMware View\Agent\bin\wsnm.exe
• C:\Program Files\Common Files\VMware\USB\vmware-usbarbitrator.exe
• C:\Program Files\VMware\VMware View\Agent\bin\ws_scripthost.exe
• C:\Program Files\VMware\VMware View\Server\appblastgateway\nssm.exe
• C:\Program Files\VMware\VMware View\Server\bin\ws_ConnectionServer.exe
• C:\Program Files\VMware\VMware View\Server\bin\wsnm.exe
• C:\Program Files\VMware\VMware View\Server\bin\ws_MessageBusService.exe
• C:\Program Files\VMware\VMware View\Server\bin\SecurityGateway.exe
• C:\Program Files\VMware\VMware View\Server\bin\ws_scripthost.exe
• C:\Program Files\VMware\VMware View\Server\bin\ws_TunnelService.exe
• C:\Program Files (x86)\VMware\JMP\nssm-2.24\nssm-2.24\win32\nssm.exe
• C:\Program Files (x86)\VMware\JMP\com\xmp\node_modules\winser\bin\nssm.exe
• C:\Program Files (x86)\VMware\VMware Horizon View Client\vmware-view.exe
• C:\Program Files (x86)\VMware\VMware Horizon View Client\wsnm.exe
• C:\Program Files (x86)\VMware\VMware Horizon View Client\bin\vmware-view-usbd.exe
• C:\Program Files (x86)\Common Files\VMware\USB\vmware-usbarbitrator64.exe

Other file extension types that should be added to the exclusion list include large flat and designed files, such as VMWare disk partition.
Scanning VMWare partitions while attempting to access them can affect session loading performance and the ability to interact with the virtual machine.
Exclusions can be configured for the directory(ies) that contain the Virtual Machines, or by excluding *.vmdk and *.vmem files.

Backup process takes longer to finish when real-time scan is enabled.
There are also instances when real-time scan detects an infected file in the volume shadow copy but cannot enforce the scan action because volume shadow copies have read-only access.

You can refer to the Knowledgebase article:

• Excluding Volume Shadow copies from OfficeScan client real-time scans.

• A Volume Shadow Copy Service (VSS) update package is available for Windows Server 2003.

Make sure the checkbox for Do not scan the directories where Trend Micro products are installed is enabled in WFBS’s Exclusion List settings (Security Settings > Antivirus/Anti-spyware > Exclusions).

Add the .bkf extension to the list of real-time scan exclusions.

To know more about Microsoft's exclusion list, refer to this TechNet article:

• Microsoft Anti-Virus Exclusion List.

• C:\Program Files (x86)\Zscaler\ZSATunnel\ZSATunnel.exe
• C:\Program Files (x86)\Tanium\Tanium Client\TaniumCX.exe
• C:\Program Files\Qualys\Qualysagent\QualysAgent.exe