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To resolve the issue, do the following steps:

  1. Open the IIS Manager.
  2. In the left pane, right-click on the Application Pools folder then click Add Application Pool.
  3. Indicate the following details:
    • Name: Trend
    • .NET CLR Version: v.4.0.xxxxx
    • Managed pipeline mode: Integrated
  4. In the left pane, expand the Application Pools.
  5. Right-click Trend, then select Advanced Settings.
  6. Scroll down to the Identity field and select Local System from the dropdown list.
  7. For the Predefined option, select Local System from the dropdown list.
  8. Click OK.
  9. In the left pane, expand the Web Sites folder.
  10. Right-click OfficeScan, then click Manage Website > Advanced Settings.
  11. For Application pool, select Trend from the dropdown list. If you get an inheritance override, select all.
  12. Click OK.
  13. Restart the IIS Admin Service. Perform the steps below:
    1. In your desktop, click Start > Run.
      Alternatively, you can press the Windows Key + R on your keyboard.
    2. In the Open field, type "services.msc", and then click OK.
    3. Look for and select IIS Admin Service, and click the Restart link, located in the left pane.
 
If an Application Pool is already configured for the OfficeScan website, check the permission of web.config to make sure that the Administrator or user logged-in has full control privileges on the file. You can also check the IIS logs to help determine the root cause if the above steps were not able to help.