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To resolve the issue:

  1. Open the Internet Information Services (IIS) Manager.
  2. Expand the server name, then click Application Pools.

    Application Pools

  3. On the right pane, click Set Application Pool Defaults.
  4. Under (General) section, change the following settings for .NET Framework Version:

    Enable 32-Bit Applications - False
    Start Automatically - False

  5. Click OK.
  6. Close IIS.
  7. Restart the following:
    • World Wide Web Publishing Service
    • Trend Micro Security Server Master Service
  8. Log on to the WFBS console. You will now be able to open it.