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ApplicationRecommendation
Other Endpoint Security SoftwareBefore installing the Security Server, Trend Micro recommends manually removing other endpoint security software from the target computer as this may block the installation or influence the Security Server’s performance later after installation.  
Security Applications in Windows SBS and EBS 2008WFBS is compatible with both Windows Small Business Server (SBS) 2008 and Windows Essential Business Server (EBS) 2008. However, some security applications that are either installed with or managed through these operating systems may conflict with WFBS. For this reason, you may need to remove these security applications.  
Messaging Security Agent and ForefrontThe Messaging Security Agent cannot be installed on Microsoft Exchange servers that have Forefront (Microsoft Forefront Security for Exchange Server) installed. Uninstall Forefront and ensure that the Microsoft Exchange Information Store service is started before installing the Messaging Security Agent.  
Security Agents and OneCareAlthough the Security Server can be installed with Microsoft Windows Live™ OneCare for Server, the Security Agent cannot be installed with the OneCare client. The Security Agent installer will automatically remove OneCare from clients.  
DatabasesScanning databases may decrease the performance of applications that access the databases. Trend Micro recommends excluding databases and their backup folders from Real-time Scan. If you need to scan a database, perform a Manual Scan or schedule a scan during off-peak hours to minimize the impact.
Other Firewall ApplicationsTrend Micro recommends removing or disabling any other firewall applications prior to installing the WFBS firewall, including:
  • Windows Internet Connection Firewall (ICF)
  • Windows Firewall (WF)
However, if you want to run ICF or any other third-party firewall, add the Trend Micro Security Server listening ports to the firewall exception list (see for information on listening ports and refer to your firewall documentation for details on how to configure exception lists).