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This issue occurs when the Transport Agents of SMEX or MSA were left installed. To resolve this, manually uninstall Scanmail Transport Agents:
  1. Open Exchange Powershell and execute this command to verify if ScanMail transport agents are still installed:
    get-transportagent
    ScanMail SMTP Receive Agent
  2. Remove the ScanMail transport agents from Exchange 2010 or 2007 by running the following commands:
    Uninstall-TransportAgent -Identity "ScanMail Routing Agent"
    Uninstall-TransportAgent -Identity "ScanMail SMTP Receive Agent"
  3. Execute this command to make sure that the ScanMail transport agents were removed:
    get-transportagent
    You should be able to start the Microsoft Exchange Transport service.