The issue occurs because all instances and virtual machines deployed from a given catalog/vApp template from vCloud Director are given the same BIOS UUID.

Because Deep Security distinguishes different VMs by their BIOS UUID, a duplicate value in the vCenter causes an "Anti-Malware Engine Offline" error to the VMs in vCloud, when integrated with Deep Security.

To resolve the issue, create a new unique uuid.bios entry. For the procedure, refer to this VMware KB article: BIOS UUIDs in vCloud Director are not unique when virtual machines are deployed from catalog templates.