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If you're using SQL Server 2019 GM Build, please upgrade your SQL server to build CU4 or above version as there is a known issue with SQL server 2019 GM which affects the communication with Apex Central.
Access the Apex Central and do the following:

  1. Reduce the client TCP/IP socket connection timeout value from the default value of 240 seconds:
    1. Start Registry Editor.
       
      Always back up the whole registry before making any modifications. Incorrect changes to the registry can cause serious system problems.
       
    2. Browse to this registry hive: HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Services\Tcpip\Parameters.
    3. Create a new REG_DWORD value named "TcpTimedWaitDelay".
    4. Set the value to "30".
  2. Extend the Socket Port number by opening Command Prompt with admin privileges and launching the following command:

    netsh int ipv4 set dynamic tcp start=25000 num=30000

  3. Reboot the machine.
  4. Try to register the Apex One server to the Apex Central server again.
If the issue persists, please contact Trend Micro Technical Support for further assistance.