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To enable Multi-Factor Authentication on new or existing Cloud App Security Service Accounts:

  1. Log in to the Office 365 Admin Center.
  2. Select the Users > Active Users tab.
  3. Select “Cloud App Security Service Account for SharePoint” from the Active Users list.

    Enable multi-factor authentication

  4. Click Manage Contact Information to update the service account with a mobile phone number for authentication purposes.

    Enable multi-factor authentication

  5. Reset the password using the "Let Me Create the Password" option.

    Enable multi-factor authentication

  6. Click Manage Multi-Factor Authentication for the User account.

    Enable multi-factor authentication

    This will redirect to the multi-factor authentication page.

  7. Select the User account and click enable multi-factor auth.

    Enable multi-factor authentication

  8. Log in to My Account using the service account name and the new password created in Step 5, and complete the multi-factor login using the code sent to the mobile phone number added in Step 4.
  9. Once the login has been verified in My Account, navigate to Security & Privacy > Additional security verification > Create and manage App Passwords.

    Enable multi-factor authentication

    Enable multi-factor authentication

  10. Click Create and name the new password "Cloud App Security".

    Enable multi-factor authentication

    Enable multi-factor authentication

    The name of the app password and the password will be shown on screen.

  11. Copy the password by clicking copy password to clipboard.

    Enable multi-factor authentication

  12. Log in to Cloud App Security and navigate to Administration > Service Account.
  13. On the SharePoint service account, select "Change Password" then paste the new app password and save it.

    Enable multi-factor authentication